1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or research is vital for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets specific different types of cancer, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the output approach and making sure high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Bortezomib Acid Impurity Lapatinib is employed to deal with breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the remedy of breast cancer. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal most cancers and smaller mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the CIS-3-HYDROXY-4-PHENYL-2-AZETIDINONE synthesis of adamantane derivatives, which have several purposes, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication employed to control form two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).